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Abstract #4270

Simultaneous Diffusion, PD, T1, and T2 Mapping with Optimized MR Fingerprinting EPI

Ouri Cohen1,2 and Matthew S. Rosen1,2

1Radiology, MGH Athinoula A. Martinos Center/Harvard Medical School, Charlestown, MA, United States, 2Physics, Harvard University, Cambridge, MA, United States

MR Fingerprinting (MRF) is a recent technique for simultaneous acquisition of multi-parametric tissue maps. Beyond the proton density (PD), T1 and T2 maps routinely obtained with conventional MRF sequences, quantitative diffusion maps are of great clinical interest but are challenging to acquire due to long scan times and poor resolution. In previous work we’ve demonstrated an optimized MRF EPI sequence that allows short scan times. Here we characterize its diffusion sensitivity and demonstrate its potential for simultaneous mapping of PD, T1, T2 and diffusion.

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