Abstract #4350

Robust Retrospective Respiratory Gating for Detection of Small Pulmonary Nodules with UTE MRI

Naoharu Kobayashi¹, Abbie Begnaud², Tadashi Allen³, Gregory J. Metzger¹, Robert Kratzke⁴, and Michael Garwood¹

¹Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ²Division of Pulmonary, Allergy, Critical Care and Sleep, Department of Medicine, University of Minnesota, Minneapolis, MN, United States, ³Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ⁴Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, United States

Retrospective respiratory gating using a 3D time series lung image reconstructed with sub-second temporal resolution is introduced to achieve accurate small pulmonary nodule detection with ultrashort echo time (UTE) MRI. Changes of the diaphragmatic level during free breathing were tracked using the 3D time series lung image. With the extracted respiratory motion, the data in exhalation were reconstructed to a high resolution image. The feasibility and robustness of the proposed retrospective gating method were tested by surveilling incident lung nodules in two UTE MRI examinations: a baseline scan and a follow-up scan in 10 weeks.

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