Abstract #4356

3D T1 mapping in the lungs during free breathing using asymmetrical cylindrical encoding

Simon MF Triphan^1,2, Mark O Wielpütz^1,2, Hans-Ulrich Kauczor^1,2, and Bertram J Jobst^1,2

¹Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany, ²Translational Lung Research Centre, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany

T1 in the lungs has been found to be interesting both for oxygen enhanced imaging and as a biomarker in COPD. In this work, T1 mapping in human lungs was implemented using a cylindrically encoded 3D measurement using asymmetric radial encoding in an inversion recovery experiment. Breathing was compensated by employing DC-gating with the MR signal, using a correction to cancel the influence of the inversion recovery. It is shown that using a segmented scheme for 3D phase encoding steps that spreads steps over k-space while minimizing leaps in T1-weighting improves gating performance and thus the resulting T1 maps.

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