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Abstract #4378

Feasibility of USPIO enhanced 7 Tesla MRI for detecting lymph node metastases in prostate cancer

Bart WJ Philips1, Rutger CH Stijns1, Sören Johst2, Stephan Orzada2, Ansje S Fortuin1, Jelle O Barentsz1, Marnix C Maas1, and Tom WJ Scheenen1

1Radiology and Nuclear Medicine, Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands, 2Erwin L. Hahn Institute for MR Imaging, University of Duisburg-Essen, Essen, Germany

Ultrahigh field MRI offers opportunities for USPIO enhanced MRI for diagnosing lymph node metastases in prostate cancer, by improving resolution and increasing the sensitivity to USPIO particles. The assessment of lymph nodes based on size, shape and USPIO uptake can improve the differentiation between non-cancer and metastatic lymph nodes and may also lower the detection size limit for metastatic nodes. In this work we show the first results of USPIO enhanced MRI and computed echo time imaging of patients with high risk prostate cancer at 7 Tesla.

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