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Abstract #4408

Development of an Asymmetrical Birdcage Design towards Homogeneous Volume Excitation for Hyperpolarized Xenon-129 Lung Imaging at 3T

Wolfgang Loew1, Christopher Ireland1, Zackary Cleveland2, Hui Wang3, Peter van der Meulen4, Randy Giaquinto1, Ronald Pratt1, Jason Woods2, and Charles Dumoulin1

1Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 2Center for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 3Philips Healthcare, Gainesville, FL, United States, 4Philips Healthcare, Best, Netherlands

Hyperpolarized 129Xe imaging is increasingly viewed as a viable tool for assessing lung structure and function. 129Xe MRI requires that large flip angle and frequency selective RF pulses be applied homogeneously across the entire thorax. The transmit performance of three common multi-nuclear whole-body birdcage designs was assessed under a loaded condition at different locations inside the RF shield with electromagnetic field simulations. The acquired data was used to develop a novel, optimized birdcage design for which the transmit performance was analyzed and compared to the three common designs.

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