Abstract #4490

Intra- and Inter-scanner Variability Evaluation of RR-VFA B1+ and T1 in the Prostate at 3T

Xinran Zhong^1,2, Dapeng Liu¹, James Sayre¹, Holden H Wu^1,2, and Kyunghyun Sung^1,2

¹Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, ²Physics and Biology in Medicine IDP, University of California, Los Angeles, Los Angeles, CA, United States

Accurate T₁ estimation is critical for quantitative prostate DCE MRI. B₁⁺ inhomogeneity can introduce significant error into the T₁ quantification, especially for variable flip angle method. Reference region variable flip angle (RR-VFA) method is a promising B₁⁺ and T₁ estimation technique, which requires no separate scans for B₁⁺mapping and can reduce slice profile and position mismatch between B₁⁺ and T₁ maps. In this study, we investigated both intra-scanner repeatability and inter-scanner reproducibility regarding B₁⁺ corrected T₁ on two 3.0 T scanners to compare RR-VFA to a commercially available B₁⁺ estimation technique. RR-VFA showed comparable intra- and inter-scanner variability to the saturated turbo FLASH based B₁⁺ estimation technique.

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