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Abstract #4493

Dynamic Contrast-Enhanced MRI of the Prostate with Single-Echo Dixon Fat Suppression

Eric G. Stinson1, Joshua D. Trzasko1, Soudabeh Kargar1, Eric A. Borisch1, Adam T. Froemming1, Akira J Kawashima2, Phillip M. Young1, and Stephen J. Riederer1

1Radiology, Mayo Clinic, Rochester, MN, United States, 2Radiology, Mayo Clinic, Scottsdale, AZ, United States

The purpose of this work was to adapt our current clinical DCE-MRI protocol to allow for single-echo Dixon fat suppression and maintain image update times <10s. Single-echo Dixon imaging with spatial resolution that matched our current clinical protocol was performed with sub-10s update times and near-optimal Dixon SNR by increasing the readout bandwidth from ±62.5 to ±83.3 kHz. Additionally, pharmacokinetic modelling results look similar to those produced from the standard DCE-MRI protocol. DCE-MRI of the prostate with single-echo Dixon fat suppression provides high spatial and temporal resolution dynamic imaging of contrast uptake without the presence of confounding fat signal.

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