The purpose of this work was to adapt our current clinical DCE-MRI protocol to allow for single-echo Dixon fat suppression and maintain image update times <10s. Single-echo Dixon imaging with spatial resolution that matched our current clinical protocol was performed with sub-10s update times and near-optimal Dixon SNR by increasing the readout bandwidth from ±62.5 to ±83.3 kHz. Additionally, pharmacokinetic modelling results look similar to those produced from the standard DCE-MRI protocol. DCE-MRI of the prostate with single-echo Dixon fat suppression provides high spatial and temporal resolution dynamic imaging of contrast uptake without the presence of confounding fat signal.
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