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Abstract #4499

The Medical College of Wisconsin 39 (MCW39): A Magnetic Resonance Image Template of the Prostate to Facilitate Group Analysis

Sean D McGarry1, Matthew Budde2, Sarah L Hurrell3, Kenneth A Ickzowski4, Michael Griffin3, Petar Duvnjak3, Kenneth Jacobsohn5, William Hall6, Mark Hohenwalter3, Andrew Nencka3, and Peter LaViolette3

1Biophysics, Medical College of Wisconsin, Wawautosa, WI, United States, 2Neurosurgery, Medical College of Wisconsin, Wawautosa, WI, United States, 3Radiology, Medical College of Wisconsin, Wawautosa, WI, United States, 4Pathology, Medical College of Wisconsin, Wawautosa, WI, United States, 5Urologic Surgery, Medical College of Wisconsin, Wawautosa, WI, United States, 6Radiation Oncology, Medical College of Wisconsin, Wawautosa, WI, United States

The Medical College of Wisconsin 39 (MCW39) template provides a common space for the analysis of prostate cancer images. The template was generated through iterative spatial registration of T2-weighted images starting with manually drawn contours as a reference point. Expert annotations of Gleason Grade were transformed into the template space, and maps of tumor probabilities reveal the spatial localization of cancer across the cohort for each grade.

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