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Abstract #4537

Detection of BOLD Response in the Limbic System to Non-invasive Stimulation of Autonomic Nervous System with SMS at 7T

Tie-Qiang Li1, Yanlu Wang1, and Masaki Fukunaga2

1Department of Medical Radiation and Nuclear Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden, 2Division of Cerebral Integration, National Institute of Physiological Sciences, Okazaki, Japan

Previous studies of clinical patients indicate that kinetic oscillatory stimulation (KOS) in nasal cavity has a positive impact on the functioning of autonomic nervous system (ANS). For better under standing of the mechanisms underlying this treatment efficacy, we used a 7T MRI system equipped with simultaneous multiple slice (SMS) imaging techniques to study the brain activation during a robust block design of KOS.The findings from the current study demonstrate that KOS is effective to induce regulatory response of the CNS control network.

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