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Abstract #4677

Utility of 3D histogram analysis of pharmacokinetics parameters using DCE-MRI for differentiating renal clear cell carcinomas from renal harmatomas

Yanping Miao1, Yang Gao1, Peng Cao1, and Lizhi Xie2

1Department of Radiology, he Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China, 2GE Healthcare, China, Beijing, China

The aim of this study was to assess if the histogram analysis of DCE-MRIphamocokinetics parameters (Ktrans)can differentiate renal tumors: renal clear cell carcinomas (RCCs) and renal harmatoma with minimal fat. Based on an 3D entire-tumour measurement, the following histogram parameters of Ktrans were derived from histogram analysis, skewness, Energy, Entropy, Uniformity, quartile5, quartile50, Frequency size and kurtosis respectively. We concluded that frequency size was the most significant parameter for predicting renal clear cell carcinoma by analyzing these data,the other parameters had no diagnostic performance.

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