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Abstract #4683

Intravoxel incoherent motion diffusion imagingĀ for grading endometrial cancer

Qi Zhang1, Xiaoduo Yu1, Han Ouyang1, and Lizhi Xie2

1Department of diagnostic radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, Beijing, China, 2GE Healthcare, China, Beijing, China

Accurate grading of endometrial cancer (EC) is invaluable owing to its relationship with the aggressiveness, prognosis, recurrence as well as its impact on treatment stratification. The differentiation of tumor correlates with the tumor density, the nuclear-to-cytoplasm ratio and microcirculation, which can be quantitatively assessed by using ADC and IVIM parameters (such as D, D* and f). The ADC, D and f values showed good or fair inverse correlation with histological grade. Therefore, IVIM DWI is a valuable supplement to predict histological grade of EC preoperatively which could contribute to treatment planning and prognosis evaluation.

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