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Abstract #4691

Investigation of correlation between IVIM and DCE-MRI on uterine cervical carcinoma

Xiaoduo Yu1, Meng Lin1, Yue Kong2, and Lizhi xie3

1National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2GE Healthcare Life Science, Beijing, China, 3GE Healthcare, MR Research China, Beijing, China

Perfusion was of great importance to access tumor properties. In this study, the potential correlations of perfusion parameters derived from IVIM (D*, f, and f D*) and DCE-MRI (Ktrans, Kep and Ve) for uterine cervical carcinoma (UCC) were investigated and were compared between pathological types. D* and f D* were positively correlated with Ktrans, Kep and Ve, respectively. Adenocarcinoma had higher f, Ktrans and Kep values than those of squamous cell carcinoma. Therefore, IVIM, as a non-invasive method, has potential to replace DCE-MRI to accurately access tumor perfusion properties, especially when perfusion differs among different pathological types of UCC.

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