Abstract #4706

Optimal combinations of b-values in computed DWI for pancreatic cancer detection

Koji Tokunaga¹, Shigeki Arizono¹, Hiroyoshi Isoda¹, Hironori Shimizu¹, Koji Fujimoto², and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, ²Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

There has been no previous report on the optimal combinations of b-values to obtain computed DWI (cDWI) with b-values above 1000 s/mm² to evaluate pancreatic cancer. This retrospective study involved 30 pancreatic cancer patients with tumor associated pancreatitis. We aimed to evaluate the optimal combination of b-values to obtain cDWI with b-value of 1500 s/mm² from the combinations of b-values between 0 and 500 s/mm² (cDWI_0-500), 0 and 1000 s/mm² (cDWI_0-1000), 500 and 1000 s/mm² (cDWI_500-1000), and all b-values (cDWI_ALL). Only cDWI_0-1000 demonstrated statistically higher tumor detectability compared to measured DWI, while image quality was preserved in cDWI_0-1000 and cDWI_ALL.

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