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Abstract #4706

Optimal combinations of b-values in computed DWI for pancreatic cancer detection

Koji Tokunaga1, Shigeki Arizono1, Hiroyoshi Isoda1, Hironori Shimizu1, Koji Fujimoto2, and Kaori Togashi1

1Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

There has been no previous report on the optimal combinations of b-values to obtain computed DWI (cDWI) with b-values above 1000 s/mm2 to evaluate pancreatic cancer. This retrospective study involved 30 pancreatic cancer patients with tumor associated pancreatitis. We aimed to evaluate the optimal combination of b-values to obtain cDWI with b-value of 1500 s/mm2 from the combinations of b-values between 0 and 500 s/mm2 (cDWI0-500), 0 and 1000 s/mm2 (cDWI0-1000), 500 and 1000 s/mm2 (cDWI500-1000), and all b-values (cDWIALL). Only cDWI0-1000 demonstrated statistically higher tumor detectability compared to measured DWI, while image quality was preserved in cDWI0-1000 and cDWIALL.

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