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Abstract #4730

Preliminary Study on the Feasibility of Simultaneously Measuring Hepatic Stiffness and Separate Water/Fat Signal Using Dual-Echo, Dixon, Spoiled-Gradient-Echo, Magnetic Resonance Elastography

Yuan Le1, Joshua Trzasko2, Kevin Glaser2, Yuxiang Zhou3, William Pavlicek1, Joseph M. Hoxworth3, Bradley D. Bolster Jr.4, Joel P. Felmlee2, Richard L. Ehman2, and Jun Chen2

1Radiology, Mayo Clinic Arizona, Scottsdale, AZ, United States, 2Radiology, Mayo Clinic, Rochester, MN, United States, 3Radiology, Mayo Clinic Arizona, Phoenix, AZ, United States, 4Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States

A novel dual-echo, Dixon MR Elastography technique was developed to simultaneously measure the liver stiffness and separate fat/water signal. Phantom tests showed that the fat signal fraction and the stiffness measured with this technique were consistent with the values measured with separate MR spectroscopy and standard MR Elastography acquisitions. Promising results were also obtained in a healthy volunteer.

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