We evaluate the clinical feasibility and image quality of breath-hold (BH) three-dimensional (3D) MRCP using a gradient and spin-echo (GRASE) technique compared to the conventional 3D respiratory-triggered (RT)-MRCP using a turbo spin-echo (TSE) sequence at 3T. Sixty-six patients underwent both 3D RT-TSE-MRCP and 3D BH-GRASE-MRCP at 3T and three radiologists independently reviewed the images. The 3D BH-GRASE-MRCP had a significantly better image quality. In detail, 3D BH-GRASE-MRCP better depicted the common bile duct, cystic duct, and bilateral 1st intrahepatic duct. The number of scans with nondiagnostic or poor image quality significantly decreased with 3D BH-GRASE-MRCP compared with 3D RT-TSE-MRCP.