Myocardial T1 mapping shows promise for the detection of cardiomyopathy. The widely-used inversion recovery based approaches, such as MOdified Look-Locker Inversion recovery (MOLLI), can only generate a single T1 map from one breathhold scan. In this study, we developed a novel FASt multi-slice myocardial T1 mapping (FAST1) approach in a single breathhold using slice-selective inversion recovery, two inversion times per slice and an advanced reconstruction approach. This technique was evaluated in a phantom as well as in healthy volunteers, and provided similar repeatability, limited precision penalty and increased spatial coverage compared to MOLLI.
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