Abstract #4777

Automatic Quantification of Left Ventricular Non-compaction using Fractal Dimension and Parametric Ratio as Geometric Markers: Numerical Simulation and Clinical Evaluation

Amol S. Pednekar¹, Carter Chu², Tobias Schlingmann³, Zili David Chu¹, Siddharth Jadhav¹, Cory Noel³, and Prakash Masand¹

¹Radiology, Texas Children's Hospital, Houston, TX, United States, ²Clements High School, Sugar Land, TX, United States, ³Cardiology, Texas Children's Hospital, Houston, TX, United States

BSSFP distinguishes the non-compacted trabeculation (NC) from compacted myocardium (C), however the current diagnostic criterion (NC/C>2.3) for left ventricular non-compaction (LVNC) suffers from subjective variability and tends to over-diagnose, especially in pediatric patients where LV trabeculation varies on a continuous spectrum. Numerical simulations estimate exponential relationship between fractal dimension (FD) and perimetric ratio (PR) with 11 times higher dynamic range for PR for the observed FD range in 30 LVNC positive and 20 negative controls. Both FD and PR indices distinguish LVNC positive from negative (p<0.0001), while the PR and FD*PR provided 6 and 11 times higher dynamic ranges respectively.

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