Abstract #4860

Advanced MRI and MRS precursors to progression in Grade II and III Glioma

Tracy L Luks¹, Yan Li¹, Marisa LaFontaine¹, Angela Jakary¹, Michael Wahl², Susan M Chang³, and Sarah J. Nelson¹

¹Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ²Radiation Oncology, University of California San Francisco, San Francisco, CA, United States, ³Neurological Surgery, University of California San Francisco, San Francisco, CA, United States

The goal of this project is to identify serial advanced imaging markers that reveal tumor progression in grade II and III gliomas prior to the Response Assessment in Neuro-Oncology Criteria (RANO) criteria for progression. Serial advanced imaging demonstrated significant changes associated with tumor activity prior to the clinical determination of tumor progression. In diffusion imaging, there were declines in nFA, and an increase in nADC in the contrast enhancing lesions. In spectroscopic imaging, there were declines in nNAA and nCRE, and increases in nCho, nLIP and nLAC.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.