Abstract #4871

Accelerated free breathing 3D cardiac T1ρ mapping in humans using compressed sensing and improved k-space reordering

Srikant Kamesh Iyer¹, Yuchi Han², Harold Litt³, and Walter R.T. Witschey³

¹Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ²Department of Medicine, University of Pennsylvania, Philadelphia, PA, United States, ³Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

Cardiac T1ρ MRI is a parametric mapping technique for imaging myocardial fibrosis and may benefit heart disease patients unable to receive contrast agents due to poor kidney function. The purpose of this work was to develop accelerated free-breathing T1ρ mapping MRI that achieves whole heart coverage with superior spatial resolution compared to 2D methods in a reasonable scan time using compressed sensing (CS). The overall hypothesis is that 3-fold accelerated free breathing 3D cardiac T1ρ MRI is feasible.

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