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Abstract #4883

Native T1 Mapping for Characterization of Acute and Chronic Myocardial Infarction in Swine: Comparison with Contrast-enhanced MRI

Xi Liu1, Zhi-gang Yang1, and Ying-kun Guo2

1Department of Radiology, West China Hospital, Sichuan University, Chengdu, China, 2Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China

Native T1 mapping is a novel technique that permits quantification of the T1 relaxation time of myocardial tissue without requiring exogenous contrast agents, it could be used as a reliable alternative to LGE in patients with severe renal insufficiency. The present study was conducted to determine and verify the clinical feasibility of native T1 mapping of AMI and CMI as a replacement for LGE and for the discrimination of AMI from CMI in Bama mini-pigs. In our study, native T1 mapping can accurately determine acute and chronic infarct areas as well as conventional LGE imaging, however, it cannot distinguish acute from chronic myocardial infarction.

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