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Abstract #4888

Assessment of Myocardial Fibrosis in Uremic Cardiomyopathy using Cardiac MR Native T1 Mapping: A Comparison with Coronary Artery Calcium Score

Shengjia Gu1 and Wenjie Yang1

1Radiology, Ruijin Hospital, Shanghai, China

Congestive heart failure is the leading cause of death in patients with end-stage renal disease. The process of this type of dysfunction is termed uremic cardiomyopathy. Extensive myocardial fibrosis, which leads the process, has also been shown to be a stronger predictor of death. Recently, anti-fibrosis has risen as a hot target in the treatment of uremic cardiomyopathy. Therefore, its urgent to find a more accurate and non-invasive method in order to meet the demand of clinic.In this study, we use the native T1 mapping to assess the level of myocardial fibrosis in ESRD patients,comparing with the Coronary Artery Calcium Score, in order to evaluate its accuracy in diagnosis uremic cardiomyopathy.

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