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Abstract #5035

Measurement of Acute Changes in Articular Cartilage T2 Relaxation Times Immediately After Exercise

Joanna Langner1, Feliks Kogan1, Bryan Haddock2, and Garry Gold1

1Radiology, Stanford University, Stanford, CA, United States, 2Nuclear Medicine, Copenhagen University Hospital, Copenhagen, Denmark

Increased joint loading is a known risk factor for progression of osteoarthritis (OA) of the knee. However, the acute effects of exercise and joint loading are still poorly understood. Quantitative MRI measures, such as T2 relaxation times, provide an opportunity to objectively study how exercise affects cartilage matrix organization and hydration. In this work, we evaluate the feasibility of measuring acute changes in T2 relaxation times immediately after exercise, in both knees simultaneously.

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