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Abstract #5085

Noninvasive Assessment of Electrical Conductivity Characteristics of Normal and Diseased Liver Using Electric Properties Tomography

Khin Khin Tha1,2, Ulrich Katscher3, Kinya Ishizaka4, Kohsuke Kudo1,2, and Hiroki Shirato2

1Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, 2Global Station for Quantum Medical Science and Engineering, Hokkaido University, Sapporo, Japan, 3Philips Research Laboratories, Hamburg, Germany, 4Department of Radiological Technology, Hokkaido University Hospital, Sapporo, Japan

The feasibility of Electric Properties Tomography (EPT) in distinguishing between the normal and diseased liver tissues was evaluated. A 2D steady state free precession sequence was used to acquire the RF transceive phase needed for a simplified version of EPT; and a total of 10 dynamic sagittal scans of the liver were obtained under single breath-hold, in 10 healthy volunteers and 11 patients with hepatic lesions. Despite the need of technical improvements, noninvasive electrical conductivity assessment of the liver by EPT was possible. Its potential utility in identifying hepatocellular carcinomas with intratumoral necrosis and/ or high vascularity was also shown.

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