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Abstract #5153

Inversion-Recovery sat-UTE sequence for short-T2 structures positive contrast generation and quantification

Lucas Soustelle1, Ericky Caldas de A. Araujo2,3, François Rousseau4, Jean-Paul Armspach1, Pierre G. Carlier2,3, and Paulo Loureiro de Sousa1

1Université de Strasbourg, CNRS, ICube, FMTS, Strasbourg, France, 2NMR laboratory, Institute of Myology, Paris, France, 3NMR laboratory, CEA/DRF/IBFJ/MIRCen, Paris, France, 4Institut Mines Télécom Atlantique, INSERM, LaTIM, Brest, France

Short-T2 structures such as myelin and cortical bone often requires the use of inversion-recovery modules in UTE sequences to provide a selective contrast in the components of interest. The sat-UTE sequence allows for an effective slice selection, and avoid issues found in commonly used 2D IR-UTE sequences concerning the use of reshaped half-radiofrequency pulses to achieve a minimal echo time. In this work, we propose to make use of an Inversion-Recovery-prepared sat-UTE sequence to provide a short-T2 positive contrast and quantification in the white matter and in the cortical bone of a fixed mouse head.

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