Abstract #5175

Water/fat separation imaging at 7T using 3D integrated SSFP

Kaibao Sun^1,2, Zhentao Zuo^1,2, Huilou Liang^1,2, Jing An³, Danny J.J. Wang⁴, and Rong Xue^1,2

¹State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, ²University of Chinese Academy of Sciences, Beijing, China, ³Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, ⁴Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States

Balanced SSFP (bSSFP) has been used as a new alternative for water-fat separation imaging due to its fast acquisition and high SNR efficiency. However, it displays characteristic banding artifacts in the presence of field inhomogeneity, especially at the 7T ultrahigh-field MRI system. Complex combination of two phase-cycled bSSFP was used to alleviate the artifact at 3T, but would take more scan time. Integrated SSFP (iSSFP), which was modified from bSSFP, was introduced to separate water and fat while removing banding artifacts in shorter scan time. iSSFP also inherited the advantages of relatively high SNR and bright fluid. 3D iSSFP with high spatial resolution may have great potential to separate water and fat in the clinical application of 7T ultrahigh-field MRI.

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