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Abstract #5187

­­­­­­Influence of fat saturation on 3D -UTE Cones T2* mapping of tendon tissue

Paul Baron1, Dirk H.J. Poot1,2, Stephan Breda1, Edwin H.G. Oei1, and Juan A. Hernandez-Tamames1

1Department of radiology and nuclear medicine, Erasmus MC, Rotterdam, Netherlands, 2Department of medical informatics, Erasmus MC, Rotterdam, Netherlands

T2* mapping of tendon tissue is important to assess tissue pathology. Fat contamination however may lead to bias in quantification of T2*. The application of fat saturation (FS) to reduce signal contamination is not straight forward, as this may influence the signal of species with short T2* and broader line-widths. Therefore, the influence of FS on T2* was investigated in tendon tissue. No influence of FS on T2* was observed in ex-vivo tendon tissue. However, in-vivo results suggest fat-contamination was present and FS may be beneficial to reduce T2* quantification bias.

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