Abstract #5217

Generation of a muscle fibre orientation atlas of the in vivo tongue

Luuk Voskuilen^1,2,3, Ludi E. Smeele^1,4, Alfons J.M. Balm^1,4, Ferdinand van der Heijden^1,5, Gustav J. Strijkers⁶, and Aart J. Nederveen²

¹Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands, ²Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, ³Department of Oral and Maxillofacial Surgery, Academic Centre for Dentistry Amsterdam and Academic Medical Center, University of Amsterdam and VU University, Amsterdam, Netherlands, ⁴Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam, Netherlands, ⁵Department of Robotics and Mechatronics, MIRA Institute, University of Twente, Enschede, Netherlands, ⁶Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

While diffusion tensor imaging based atlases in the brain are common, no muscle fibre atlases for the tongue have been created. An unbiased atlas was generated from ten healthy volunteers, by iteratively registering fibre orientation distributions calculated via constrained spherical deconvolution to a template. The atlas shows good reproducibility and better performance than an image intensity based atlas. Various tongue muscles can be detected in tractography of the atlas. This atlas may facilitate automatic segmentation of tongue muscles after tumour resection to evaluate impaired tongue function.

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