Ischemic stroke of the brain stem affects a considerable number of human patients. However, mechanisms of degeneration and recovery are not well understood and animal models of brain stem ischemia are rare compared to models of cortical stroke. Here we implemented a rat model of brain stem ischemia and applied diffusion tensor MR imaging as a noninvasive means to assess structural connectivity. Probabilistic mapping and histology indicate structural remodeling at the level of thalamus. These results add evidence for a potential compensatory mechanism for the observed partial recovery after brain stem stroke.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords