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Abstract #5326

Highly efficient diffusion MRI by Slice-interleaved Free-waveform Imaging (SIFI)

Jana Hutter1, Markus Nilsson2, Daan Christiaens1, Torben Schneider3, Anthony N Price1, Joseph V Hajnal1, and Filip Szczepankiewicz2,4

1Biomedical Engineering, King's College London, London, United Kingdom, 2Clinical Sciences, Lund University, Lund, Sweden, 3Philips Healthcare, Guilford, United Kingdom, 4Random Walk Imaging AB, Lund, Sweden

Diffusion encoding along multiple directions in a single shot facilitates probing of tissue microstructure that is not accessible with conventional (linear) tensor encoding. However, it tends to engage gradients on multiple axes in a pattern that yields higher energy consumption, which can become a critical limiting factor for gradient system performance. Here, we show that Slice Interleaved Free-waveform Imaging (SIFI) of b-tensor size, orientation, and shape reduces peak power consumption and heating, which translates to markedly reduced repetition time, shorter examination times and higher temporal SNR.

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