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Abstract #5333

SPIRiT-Based Reconstruction of Interleaved Multi-shot EPI (SPECTRA) for Navigator-Free Diffusion Weighted MRI

Gaojie Zhu1, Hai Luo1, Xiang Zhou1, Meining Chen1, Chao Wang1, Wei Bian2, and Ziyue Wu1

1Advanced Application, Alltech Medical Systems, Chengdu, China, 2Alltech Medical Systems, Chengdu, China

Multi-shot EPI can achieve a high imaging resolution for Diffusion weighted MRI (DWI) by sampling a large k-space without increasing the degree of T2* blurring. However, its shot-to-shot phase error has to be corrected. Recently, a navigator-free correction method based on SENSE technique has been developed, assuming the phase error is spatially smooth among different DWI shots. In this work, we propose a SPIRiT-based method to correct the phase error and iteratively reconstruct navigator-free multi-shot EPI. Our results suggest it has the advantage of insensitivity to coil map bias and better SNR compared to the SENSE-based method.

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