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Abstract #5341

Comparison of Navigator-free Multi-shot Diffusion-Weighted Imaging Reconstruction Algorithms for EPI

Malte Steinhoff1,2, Kay Nehrke3, and Peter Börnert3,4

1Braunschweig University of Technology, Braunschweig, Germany, 2University of Lübeck, Lübeck, Germany, 3Philips Research Europe, Hamburg, Germany, 4Dept. Radiology, LUMC, Leiden, Netherlands

Multi-shot diffusion-weighted MRI allows for higher spatial resolution than single-shot approaches, but suffers from image artifacts due to motion-induced shot-specific phase variations. Advanced parallel imaging reconstructions can mitigate these effects, but a comparison of these approaches is still missing, especially for the widespread EPI. Following the concept of reproducible research, a number of algorithms were implemented, adapted and refined for EPI, and compared in simulations and in-vivo. Results show different performance and applicability. The iterative feedback and the sharing of joint global information in the reconstruction and appropriate constraints were found to be crucial for high-quality high-resolution DWI.

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