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Abstract #5400

Quantitative MR Neurography with Robust Fat Suppression

Masami Yoneyama1, Akio Hiwatashi2, Xinzeng Wang3, Osamu Togao2, Ivan E. Dimitrov4,5, Ananth J. Madhuranthakam3,4, Iain Ball6, and Marc Van Cauteren7

1Philips Japan, Tokyo, Japan, 2Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 3Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States, 4Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, 5Philips Healthcare, Gainesville, FL, United States, 6Philips Healthcare Australia, North Ryde, Australia, 7Philips Healthcare Asia Pacific, Tokyo, Japan

MR neurography plays a major role in the diagnostic work-up of peripheral nerve pathologies and a quantitative evaluation based on T2 values can be clinically useful in estimating treatment effects and determining prognosis. Recently, we proposed a new sequence (SHINKEI-Quant) to add a quantitative information to MR neurography. To solve some issues caused by the current fat suppression techniques (SPAIR and STIR), we propose to combine SHINKEI-Quant with a new two-point dual-echo 3D DIXON-TSE (DE-mDIXON) technique. SHINKEI-Quant with DE-mDIXON simultaneously provides both MR neurography with high SNR, uniform fat suppression, and T2 maps with T2 values similar to conventional method. This sequence may be helpful to quantitatively assess nerve pathology.

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