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Abstract #5441

High SNR Functional MRI Using Oscillating Steady State Imaging

Shouchang Guo1 and Douglas C. Noll2

1Electrical and Computer Engineering, University of Michigan, Ann Arbor, MI, United States, 2Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Signal-to-noise ratio (SNR), a limiting factor for functional MRI, can be improved by through the use of higher magnetic fields or through the use of array coils. This work proposes a novel acquisition scheme for BOLD fMRI that has the potential to improve SNR by a factor of 2 or more. This approach uses an oscillating steady state signal that is T2*-weighting and when combined across the period of oscillation produced robust fMRI results in both 2D and 3D imaging experiments.

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