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Abstract #5444

Enhanced fMRI Using a Novel 3D Ultrafast Gradient-echo-based Sequence Using Spatiotemporal Encoding.

JaeKyun Ryu1,2, Won Beom Jung1,2, Jeong Pyo Son1, Seong-gi Kim1,2, and Jang-Yeon Park1,2

1Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Republic of Korea, 2Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Republic of Korea

We recently introduced a novel ultrafast 3D gradient-echo-based imaging technique using spatiotemporal encoding (SPEN), which was dubbed RASE (Rapid Acquisition with Sequential Excitation). RASE has less sensitivity to field inhomogeneities and susceptibility differences compared to conventional multi-slice GE-EPI, sharing the advantages of 3D imaging such as high signal-to-noise ratio and high spatial resolution. In this preliminary study, we present very promising results of RASE-II fMRI, i.e., better t-scores, tSNR, and BOLD percent-signal-changes than conventional multi-slice GE-EPI, on a 9.4-T animal scanner.

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