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Abstract #5462

Mouse auditory pathway mapping using BOLD fMRI coherence analysis

Cristina Chavarrias1, Guilherme Blazquez Freches1, and Noam Shemesh1

1Champalimaud Neuroscience Programme, Lisbon, Portugal

The feasibility and potential of mapping the mouse auditory system through functional magnetic resonance imaging (fMRI) in mice was recently demonstrated. The goal of this work was to compare the conventional GLM analysis, which relies on the variability across regions of the haemodynamic response, with a coherence analysis, which is data-driven and provides rich temporal information. Coherence amplitudes closely follow the pattern of the GLM maps, whereas the delay maps obtained from the coherence phase show different latencies even inside each ROI. This suggests the utility of coherence analysis for mapping the auditory pathway in-vivo.

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