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Abstract #5497

Immunohistochemical validation of myelin water fraction obtained with FAST-T2 at 3 Tesla

Thanh D Nguyen1, Mayyan Mubarak2, Somiah Dahlawi2, Kelly M Gillen1, David Pitt2, and Yi Wang1

1Weill Cornell Medical College, New York, NY, United States, 2Yale University, New Haven, CT, United States

The purpose of this study was to validate MWF measurements obtained by FAST-T2 at 3T by myelin basic protein (MBP) staining in a postmortem brain. Excellent correlation (R=0.98) was found between MWF and MBP relative optical density measurements.

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