Abstract #5540

A correlation of resting state DfMRI signals reflects functional connectivity in awake mouse

Yoshifumi Abe¹, Yuki Sakai², Hiroaki Hamada³, Norio Takata¹, Kenji Doya³, and Kenji Tanaka¹

¹Departemnt of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan, ²ATR Brain Information Communication Research Laboratory Group, Kyoto, Japan, ³Neural Computation Unit and Biological Physics Theory unit, Okinawa Insititute of Science and Technology, Okinawa, Japan

Diffusion fMRI (DfMRI) is an imaging method to investigate brain activity regardless of hemodynamic state. The previous study has proposed that resting state DfMRI (rsDfMRI) is suitable to investigate a magnitude of basal activity. In this study, we examined our hypothesis that this rsDfMRI have a potential of detecting functional connectivity (FC). FC patterns were compared between rsDfMRI and BOLD-rsfMRI in awake mice. A strong correlation of the pattern between rsDfMRI and BOLD-rsfMRI indicated that rsDfMRI is possible to conduct FC analysis. Therefore, we propose that rsDfMRI is a powerful tool to detect brain network as well as brain activity.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.