ZOOMit blood oxygen level dependent fMRI (ZOOMit-BOLD) can excite only a small field of view using simultaneous parallel radiofrequency pulse sequences. It provides high spatial resolution while minimizing aliasing artifacts. This prospective study compared the clinical performances of ZOOMit-BOLD and conventional-BOLD in pre-surgical hand motor function localization. Compared with conventional EPI-based BOLD acquisition, ZOOMit-BOLD is a reliable technology with higher accuracy in preoperative motor functional localization in clinical patients with gliomas, particularly when the glioma directly invades the primary motor cortex.
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