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Abstract #5590

Clinical Validation of a Semiautomated Workflow for MR Elastography

Bogdan Dzyubak1, Sudhakar K Venkatesh1, Glaser J Kevin1, and Richard L. Ehman1

1Radiology, Mayo Clinic, Rochester, MN, United States

Magnetic Resonance Elastography (MRE) is a validated method for staging hepatic fibrosis utilizing MR images of acoustic wave propagation in the liver to measure hepatic stiffness. A new MRE analysis workflow, called ALEC, in which readers are presented with preliminary, automatically generated, ROIs was validated in a clinical environment using 1347 exams. The workflow failed in <1% of cases. Manual modification was performed on 18% of the exams, leading to a stiffness change of only 1% on average. The ALEC-assisted stiffness measurement workflow offers a faster and more reproducible way to perform MRE.

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