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Abstract #5617

Single Breath-hold 3D T2-weighted bSSFP Imaging (T2-TIDE) for Treatment Planning on a Low-field MRI-guided Radiotherapy System

Yu Gao1,2, Fei Han1, Ziwu Zhou1, Jiaxin Shao1, Percy Lee3, Ann Raldow3, Daniel A Low2,3, Yingli Yang2,3, and Peng Hu1,2

1Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2Physics and Biology in Medicine IDP, University of California, Los Angeles, Los Angeles, CA, United States, 3Department of Radiation Oncology, University of California, Los Angeles, Los Angeles, CA, United States

A T2-transition into driven equilibrium (T2-TIDE) technique along with compressed sensing reconstruction was proposed to generate 3D T2-weighted images in a single breath-hold for radiotherapy treatment planning on a low-field MRI-guided radiotherapy system. Phantom and volunteer studies were performed to determine the optimal parameters that provided the best contrast. Five patients with abdominal tumors were recruited to compare the proposed T2-TIDE technique with the conventional bSSFP approach. Improved tumor/organ contrast were observed for all five patients, indicating the superior quality of T2-TIDE technique for tumor/organ delineation.

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