Abstract #5641

Simultaneous mapping of R2*, T1, and proton density fat fraction for the liver: single breath-hold acquisition with multi-echo spoiled gradient echo and compressed sensing

Daiki Tamada¹, Tetsuya Wakayama², Utaroh Motosugi¹, and Hiroshi Onishi¹

¹Department of Radiology, University of Yamanashi, Chuo, Japan, ²GE Healthcare Japan, Hino, Japan

In this study, we developed multi-parameter mapping including T1, R2*, and proton density fat fraction with a single breath-hold, to evaluate liver disease and liver function. Six-echo spoiled gradient echo sequence with dual flip angles was used to acquire a 12-set MRI volume dataset. To shorten the scan time, undersampling and multi-contrast compressed sensing reconstruction were used. Quantitative values were validated by performing phantom and volunteer studies.

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