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Abstract #5641

Simultaneous mapping of R2*, T1, and proton density fat fraction for the liver: single breath-hold acquisition with multi-echo spoiled gradient echo and compressed sensing

Daiki Tamada1, Tetsuya Wakayama2, Utaroh Motosugi1, and Hiroshi Onishi1

1Department of Radiology, University of Yamanashi, Chuo, Japan, 2GE Healthcare Japan, Hino, Japan

In this study, we developed multi-parameter mapping including T1, R2*, and proton density fat fraction with a single breath-hold, to evaluate liver disease and liver function. Six-echo spoiled gradient echo sequence with dual flip angles was used to acquire a 12-set MRI volume dataset. To shorten the scan time, undersampling and multi-contrast compressed sensing reconstruction were used. Quantitative values were validated by performing phantom and volunteer studies.

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