Abstract #5646

An investigation into the effect of body composition on the agreement between whole-body fat mass determined by MRI and air-displacement plethysmography.

Andrew Weedall¹, Adrian Wilson^2,3, and Sarah Wayte¹

¹Department of Clinical Physics and Bioengineering, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, ²Research and Development Department, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom, ³Department of Physics, University of Warwick, Coventry, United Kingdom

The agreement between whole-body fat mass determined using MRI and air-displacement plethysmography (ADP) was investigated for a range of non-pathological body mass indexes (BMIs). The whole-body fat mass was determined for ten volunteers by two methods: firstly by ADP using a BODPOD^®; and secondly using two different MRI sequences (LAVA-flex and IDEAL IQ). The whole-body fat mass determined by both MRI protocols showed good agreement with, but were consistently higher than, the ADP determination (mean difference: LAVA-flex=4±3kg; IDEAL IQ=2±3kg). In addition, analysis of Bland-Altman plots showed no change in the differences between the MRI and ADP fat mass with BMI.

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