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Abstract #0070

Free-breathing placental and fetal MR angiography using continuous stable state acquisition (Sweep)

Laurence H Jackson1, Anthony N Price1, Jana Hutter1, Alison Ho2, Thomas A Roberts1, Laura McCabe1,3, Maria Deprez1, Lucy Chappell2, Mary Rutherford1,3, and Joseph V Hajnal1,3

1Biomedical Engineering,School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom, 2Department of Women and Children’s Health, School of Life Course Sciences, Kings College London, London, United Kingdom, 3Centre for the Developing brain, School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom

Major obstetric complications such as pre-eclampsia and intrauterine growth restriction can result from malformations in the circulation of the fetus and placenta. Robust, high resolution in-utero MR angiography has the potential to be a valuable tool in identification and monitoring of these disorders but is hampered by the presence of complex motion, ineffective breath holds and lack of safe contrast agents. Here we present a motion compensated method for visualising the vascular networks in the fetus and placenta using respiration resolved 2D inflow angiography with efficient and dense spatiotemporal sampling and retrospective correction.

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