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Abstract #0072

Motion-insensitive 3D T2*-weighted MRI using a motion- and B0 field-navigator

Jiaen Liu1, Peter van Gelderen1, Jacco A. de Zwart1, and Jeff H. Duyn1

1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States

The ability of T2*-weighted (or susceptibility-weighed) MRI to provide structural and functional information about the brain is affected by B0 field fluctuations associated with head motion, which are inadequately accounted for in current correction approaches. Here, a 3D EPI navigator was developed to measure head motion, map the associated complex B0 field changes and correct their effects in T2*-weighted GRE MRI. Adequate temporal resolution of the navigator was achieved by implementing 2D parallel imaging with controlled aliasing. A fast reconstruction strategy is proposed to retrospectively correct the motion artifacts, overcoming limitations of prospective B0 corrections inadequately dealing with the spatially complex B0 changes.

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