Recent advances have enabled fully self-gated high resolution imaging using a Free-running framework, where data is continuously collected, retrospectively binned into cardiac and respiratory phases, and reconstructed using multi-dimensional compressed sensing (CS) for efficient functional and anatomical imaging of the heart. Here, we propose a novel expansion of this framework to cardiac and respiratory motion-resolved 3D flow imaging— or 5D flow MRI. The findings of this study show that 5D flow MRI is feasible in-vitro and in-vivo and can depict cardiac and respiratory-resolved 3D hemodynamics.
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