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Abstract #0090

5D flow MRI: A free-running, fully self-gated, radial imaging framework for cardiac and respiratory motion-resolved assessment of 3D blood flow dynamics

Liliana Ma1,2, Jérôme Yerly3, Christopher W Roy3, Davide Piccini3,4, Lorenzo Di Sopra3, James Carr1, Matthias Stuber3, and Michael Markl1,2

1Radiology, Northwestern University, Chicago, IL, United States, 2Biomedical Engineering, Northwestern University, Evanston, IL, United States, 3Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 4Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland

Recent advances have enabled fully self-gated high resolution imaging using a Free-running framework, where data is continuously collected, retrospectively binned into cardiac and respiratory phases, and reconstructed using multi-dimensional compressed sensing (CS) for efficient functional and anatomical imaging of the heart. Here, we propose a novel expansion of this framework to cardiac and respiratory motion-resolved 3D flow imaging— or 5D flow MRI. The findings of this study show that 5D flow MRI is feasible in-vitro and in-vivo and can depict cardiac and respiratory-resolved 3D hemodynamics.

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