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Abstract #0096

Technical Feasibility of Three-Dimensional Magnetic Resonance Elastography for Assessing Endometrial Carcinoma

Xi Long1, Tianhui Zhang1, Sichi Kuang1, Ying Deng1, Bingjun He1, Jingbiao Chen1, Phillip Rossman2, Kevin J Glaser2, Sudhakar K Venkatesh2, Bing Wu3, Richard L Ehman2, and Jin Wang1

1Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, 2Department of Radiology, Mayo Clinic, Rochester, MN, United States, 3MR Research China, GE Healthcare, Beijing, China

Endometrial carcinoma (EC) is one of the most common primary malignant tumors in women worldwide. Tumor grades, International Federation of Gynecology and Obstetrics (FIGO) stage and myometrial invasion of EC are important factors for treatment planning and prognosis. We explored the potential value of MR elastography (MRE) for the prediction of tumor grades, FIGO stage and myometrial invasion of EC. Our study showed that mean tumor stiffness may be a useful metric for differentiating well or moderately differentiated EC from poorly differentiated EC and for differentiating superficial invasion from deep myometrial invasion in EC.

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