Abstract #0096

Technical Feasibility of Three-Dimensional Magnetic Resonance Elastography for Assessing Endometrial Carcinoma

Xi Long¹, Tianhui Zhang¹, Sichi Kuang¹, Ying Deng¹, Bingjun He¹, Jingbiao Chen¹, Phillip Rossman², Kevin J Glaser², Sudhakar K Venkatesh², Bing Wu³, Richard L Ehman², and Jin Wang¹

¹Department of Radiology, The third affiliated hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Radiology, Mayo Clinic, Rochester, MN, United States, ³MR Research China, GE Healthcare, Beijing, China

Endometrial carcinoma (EC) is one of the most common primary malignant tumors in women worldwide. Tumor grades, International Federation of Gynecology and Obstetrics (FIGO) stage and myometrial invasion of EC are important factors for treatment planning and prognosis. We explored the potential value of MR elastography (MRE) for the prediction of tumor grades, FIGO stage and myometrial invasion of EC. Our study showed that mean tumor stiffness may be a useful metric for differentiating well or moderately differentiated EC from poorly differentiated EC and for differentiating superficial invasion from deep myometrial invasion in EC.

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