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Abstract #0099

Three-Dimensional Amide Proton Transfer MR Imaging for Cervical Cancer: Initial Experience

Yong-Lan He1, Cheng-Yu Lin1, Ya-Fei Qi1, Xiaoqi Wang2, Hai-Long Zhou1, Hua-Dan Xue1, and Zheng-Yu Jin1

1Peking Union Medical College Hospital, Beijing, China, 2Philips Healthcare China, Beijing, China

The present study demonstrates the feasibility of 3D APT MR imaging for uterine cervix on the largest sample size to our knowledge. As the clinical robustness of APT imaging in the pelvis is what researchers concerned, our study investigated and revealed the excellent agreement in both image quality assessment and APT values measurement, even on small cervical lesions with maximum diameter less than 2cm. Our studies demonstrated that APT imaging could differentiate cervical cancer from normal cervix. Cervical cancer showed significant higher APT values than that of normal cervix.

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