Abstract #0102

The feasibility of matching lymph nodes detected on USPIO-enhanced MRI with histopathology in rectal cancer

Rutger C.H. Stijns¹, Bart W.J. Philips¹, Iris D. Nagtegaal², Fatih Polat³, Johannes H.W. de Wilt⁴, Carla A.P. Wauters⁵, Patrik H.W. Zamecnik⁶, Jurgen J. Futterer¹, and Tom W.J. Scheenen¹

¹Radiology, Radboudumc, Nijmegen, Netherlands, ²Pathology, Radboudumc, Nijmegen, Netherlands, ³Surgery, Cansius-Wilhelmina hospital, Nijmegen, Netherlands, ⁴Surgery, Radboudumc, Nijmegen, Netherlands, ⁵Pathology, Cansius-Wilhelmina hospital, Nijmegen, Netherlands, ⁶Radboudumc, Nijmegen, Netherlands

Lymph node staging in rectal cancer based on imaging is a major challenge. Node-to-node matching is crucial to determine the histopathology of lymph nodes that are detected on in-vivo MRI. A workflow of in-vivo MRI, ex-vivo MRI and MR-guided pathology was set up for lymph nodes that were characterized on USPIO-enhanced MRI. Difficulties were seen in the node-to-node matching, in despite of the use of high-resolution 3D ex-vivo MRI to link in-vivo detected nodes to final pathology.

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