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Abstract #0104

Ex-vivo MR-guided pathology to improve lymph node staging in rectal cancer

Rutger C.H. Stijns1, Bart W.J. Philips1, Carla A.P. Wauters2, Johannes H.W. de Wilt3, Iris D. Nagtegaal4, and Tom W.J Scheenen1

1Radiology, Radboudumc, Nijmegen, Netherlands, 2Pathology, Canisius-Wilhelmina hospital, Nijmegen, Netherlands, 3Surgery, Radboudumc, Nijmegen, Netherlands, 4Pathology, Radboudumc, Nijmegen, Netherlands

Pathological lymph node yield can be influenced by multiple factors. The use of ex-vivo MR guided pathology of rectal specimens could provide insight in the number and size of lymph nodes present in a rectal specimen and aid in an increased pathological lymph node yield. Therefore two series of rectal specimens were examined, one control group and one MR-guided group. Ex-vivo­ MRI revealed significantly more and significantly smaller lymph nodes without increasing the pathological yield. Small nodes appear to be difficult to harvest, presumably requiring a 3D approach for further improvement of pathological evaluation.

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