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Abstract #0132

Denoising of Diffusion MRI Improves Peripheral Nerve Conspicuity and Reproducibility

Jaemin Shin1, Jahnavi Curlin2, Ek Tsoon Tan3, Maggie Fung1, and Darryl Sneag2

1GE Healthcare, New York, NY, United States, 2Hospital for Special Surgery, New York, NY, United States, 3GE Global Research, Niskayuna, NY, United States

This study evaluated q-space-based (genSD) and principal component analysis (PCA) denoising techniques to enhance SNR for peripheral nerve diffusion MRI of 10 healthy knees. The combination of both methods (PCA+genSD) was compared with a PCA-only method as well as the average of 10 repetitions. The combined denoising method showed improved performance with respect to SNR, peripheral nerve conspicuity and reproducibility.

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